Focal limbal stem cell deficiency corresponding to an iris coloboma
نویسندگان
چکیده
منابع مشابه
Focal limbal stem cell deficiency corresponding to an iris coloboma.
When the stem cells population is destroyed or their supporting stromal environment is dysfunctional, limbal stem cell deficiency (LSCD) manifests. Clinically, LSCD carries the hallmark of conjunctivalisation— that is, the corneal surface is covered by ingrowing conjunctival epithelium containing goblet cells. Conjunctivalisation is invariably associated with the destruction of the basement mem...
متن کاملLong-term Outcome of Limbal Stem Cell Transplantation for the Management of Total Limbal Stem Cell Deficiency due to a Chemical Burn
Purpose: To evaluate the long-term outcome of limbal stem cell transplantation (LSCT) for the management of total limbal stem cell deficiency (LSCD) due to chemical burn in Labbafinejad Medical Center (LMC). Methods: Records of patients with a history of severe (i.e. grade III and IV) chemical burns, who were referred to LMC and underwent LSCT, were reviewed and data including demographic chara...
متن کاملMinimal conjunctival limbal autograft for total limbal stem cell deficiency.
PURPOSE To report the results of one 60 degrees conjunctival limbal autograft (CLAU) combined with amniotic membrane (AM) transplantation for an eye with total limbal stem cell deficiency (LSCD). METHODS One eye of a patient with chronic total LSCD and symblepharon caused by chemical burn was subjected to symblepharon lysis, removal of pannus from corneal surface, AM transplantation to cover ...
متن کاملAllo-limbal transplantation in patients with limbal stem cell deficiency.
AIM To report the outcome of a series of patients with stem cell deficiency who underwent allo-limbal transplantation and to describe a technique for this procedure. METHODS Six consecutive patients underwent allo-limbal stem cell transplantation. The primary diagnosis included alkali burn (n = 2), trachoma (n = 1), chronic rosacea blepharitis and kerato-conjunctivitis (n = 1), aniridia (n = ...
متن کاملLimbal Stem Cell Deficiency and Treatment with Stem Cell Transplantation
The cornea is the outermost tissue of the eye and it must be transparent for the maintenance of good visual function. The superficial epithelium of the cornea, which is renewed continuously by corneal stem cells, plays a critical role in the permanence of this transparency. These stem cells are localized at the cornea-conjunctival transition zone, referred to as the limbus. When this zone is af...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 2002
ISSN: 0007-1161
DOI: 10.1136/bjo.86.12.1451